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Primary infection by Pneumocystis induces Notch-independent Clara cell mucin production in rat distal airways

Clara cells are the main airway secretory cells able to regenerate epithelium in the distal airways through transdifferentiating into goblet cells, a process under negative regulation of the Notch pathway. Pneumocystis is a highly prevalent fungus in humans occurring between 2 and 5 months of age, a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Méndez, Andrea, Rojas, Diego A., Ponce, Carolina A., Bustamante, Rebeca, Beltrán, Caroll J., Toledo, Jorge, García-Angulo, Victor A., Henriquez, Mauricio, Vargas, Sergio L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553854/
https://ncbi.nlm.nih.gov/pubmed/31170201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217684
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