Highly active C8-acyl-ACP thioesterase variant isolated by a synthetic selection strategy

Microbial metabolism is an attractive route for producing medium chain-length fatty acids, e.g. octanoic acid, used in the oleochemical industry. One challenge to this strategy is the lack of enzymes that are both highly active in a microbial host and selective towards substrates with desired chain-...

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Publicado en:ACS Synth Biol
Main Authors: Hernández Lozada, Néstor J., Lai, Rung-Yi, Simmons, Trevor R., Thomas, Kelsey A., Chowdhury, Ratul, Maranas, Costas D., Pfleger, Brian F.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553638/
https://ncbi.nlm.nih.gov/pubmed/30064208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.8b00215
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