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Screening Mycobacterium tuberculosis Secreted Proteins Identifies Mpt64 as a Eukaryotic Membrane-Binding Bacterial Effector

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, is one of the most successful human pathogens. One reason for its success is that Mtb can reside within host macrophages, a cell type that normally functions to phagocytose and destroy infectious bacteria. However, Mtb is able to...

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Veröffentlicht in:mSphere
Hauptverfasser: Stamm, Chelsea E., Pasko, Breanna L., Chaisavaneeyakorn, Sujittra, Franco, Luis H., Nair, Vidhya R., Weigele, Bethany A., Alto, Neal M., Shiloh, Michael U.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553557/
https://ncbi.nlm.nih.gov/pubmed/31167949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00354-19
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