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SUN-096 Hypothalamic ATP Has a Crucial Role in the Pathogenesis of Leptin Resistance: A Potential Mechanism for the Amelioration of Leptin Resistance by Celastrol and Withaferin A
Leptin is an adipocyte-derived hormone involved in the regulation of food intake and energy expenditure. Since obese subjects generally have leptin resistance, leptin sensitizers are expected as anti-obesity drugs. It has been reported that endoplasmic reticulum (ER) stress in the hypothalamus plays...
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| Publicado no: | J Endocr Soc |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6553405/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SUN-096 |
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