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SUN-528 The Clinical Utility of Gene Sequencing in Hypophosphatasia: Lessons from Patients with Two Rare Variants

Objectives: Hypophosphatasia (HPP) is a syndrome marked by low serum alkaline phosphatase (AlkP) activity along with clinical manifestations varying from seizures to frequent fractures. Diagnosis of HPP is complicated both by its variable clinical phenotype and variable age of onset - patients are o...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Tilden, Daniel, Ramirez, Andrea, Sheehan, Jonathan, Smith, Derek, Newman, John, Dahir, Kathryn
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553214/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SUN-528
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