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SUN-035 Performance of Mutation Pathogenicity Prediction Tools on Missense Variants Associated with 46XY Disorders of Sex Development

INTRODUCTION: Single nucleotide variants (SNV) are the most common type of genetic variation among humans. The high-throughput sequencing methods increase the number of identified variants in the human genome but functional studies for disease-associated variants is laborious and time consuming. Dif...

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Pubblicato in:J Endocr Soc
Autori principali: Montenegro, Luciana, Lerario, Antonio, Nishi, Mirian, Mendonca, Berenice
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553019/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SUN-035
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