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Automated glycan assembly of Lewis type I and II oligosaccharide antigens

Human blood group related glycan antigens are fucosylated (neo-)lactoseries oligosaccharides that play crucial roles in pathogenic processes. Lewis type-II-chain antigens mark the surface of cancer cells, but are also mediators of bacterial infections. To investigate the biological roles of Lewis ty...

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Bibliographic Details
Published in:Chem Sci
Main Authors: Guberman, Mónica, Bräutigam, Maria, Seeberger, Peter H.
Format: Artigo
Language:Inglês
Published: Royal Society of Chemistry 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552968/
https://ncbi.nlm.nih.gov/pubmed/31293748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc00768g
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