SUN-229 The Role of Testosterone in Spermatogenesis: Lessons from Proteome Profiling of Human Spermatozoa in Testosterone Deficiency

Testosterone is required during spermatogenesis to mantain the blood-testis barrier and for meiosis, Sertoli-spermatid adhesion and sperm release. Aim of the study was to better understand the effect of hypothalamic-pituitary-testicular axis on sperm protein composition and function.12 male patients...

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Veröffentlicht in:J Endocr Soc
Hauptverfasser: Grande, Giuseppe, Barrachina, Ferran, Soler-Ventura, Ada, Jodar, Meritxell, Mancini, Francesca, Marana, Riccardo, Bianchi, Antonio, Pontecorvi, Alfredo, Oliva, Rafael, Milardi, Domenico
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2019
Schlagworte:
Reproductive Endocrinology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552873/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SUN-229
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