SAT-204 Silencing of Maternal Hepatic Glucocorticoid Receptor Is Essential for Normal Fetal Development

Excessive or chronic stress can lead to a variety of diseases due to aberrant activation of the glucocorticoid receptor (GR), a ligand activated transcription factor. Pregnancy represents a particular window of sensitivity in which excessive stress can have adverse outcomes, particularly on the deve...

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Udgivet i:J Endocr Soc
Main Authors: Quinn, Matthew, McCalla, Amy, He, Bo, Xu, Xiaojiang, Cidlowski, John
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2019
Fag:
Reproductive Endocrinology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552225/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-204
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