SAT-530 Establishment of a Glucocorticoid (GC) Regimen to Induce Both Growth Retardation and Osteoporosis in C57BL/10 Muscular Dystrophy Mouse Models

Glucocorticoids (GCs) are associated with many adverse effects including osteoporosis and growth retardation. These are particular problems in Duchenne muscular dystrophy (DMD) where GCs form the mainstay of treatment. The mechanisms that underlie the undesirable effects of GCs on skeletal developme...

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Udgivet i:J Endocr Soc
Main Authors: Wood, Claire, Wong, Jarod Sze Choong, Straub, Volker, Ahmed, S, Farquharson, Colin
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2019
Fag:
Bone and Mineral Metabolism
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552208/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-530
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