SAT-LB076 T2-Signal Intensity, SST Receptor Expression and First-Generation Somatostatin Analogues Efficacy Predict Hormone and Tumor Responses to Pasireotide in Acromegaly

Background: Previous studies indicate that PAS-LAR can achieve control of insulin-like growth factor I (IGF-I) levels and may reduce tumor size, however a subset of acromegaly patients responds poorly. T2-signal intensity, somatostatin receptor (SST) subtype 2 and 5 expression, and the response to f...

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Bibliographische Detailangaben
Veröffentlicht in:J Endocr Soc
Hauptverfasser: Coopmans, Eva, Schneiders, Joppe, El-Sayed, Nour, Muhammad, Ammar, Hofland, Leo, Petrossians, Patrick, Lelij, Aart., Neggers, Sebastian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2019
Schlagworte:
Neuroendocrinology and Pituitary
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552185/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-LB076
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