SAT-172 Continuous, Prolonged Treatment with the Oligonucleotide IMT504 in Diabetic NOD Mice Greatly Improves All Parameters of the Diabetic Condition

We have shown that the immunomodulatory oligonucleotide IMT504 (IMT) induces a marked recovery of single-dose streptozotocin (STZ)-induced toxic diabetes in rats that correlates with early expression of progenitor cell markers but without altering immune parameters. IMT also improves the diabetic co...

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Vydáno v:J Endocr Soc
Hlavní autoři: Bianchi, Stefania, Lavignolle Heguy, María, Montaner, Alejandro, Libertun, Carlos, Lux-Lantos, Victoria, Bianchi, Maria
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2019
Témata:
Diabetes Mellitus and Glucose Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552137/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-172
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