SAT-356 Differential Effects of Lipophilic and Hydrophilic Statins on Aldosterone Biosynthesis

Statin therapy, which lowers LDL cholesterol, has a profound beneficial cardiovascular (CV) effect. However, some of statins’ CV benefits appear to be independent of decreases in LDL. We showed that statins reduce Aldosterone (ALDO) levels, a key hormone in cardiovascular function, and this effect w...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Maris, Stephen, Lee, Jessica, Tay, Chee Sin, Zagoren, Eleanor, Garza, Amanda, Pojoga, Luminita, Romero, Jose, Williams, Gordon, Adler, Gail
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2019
Assuntos:
Adrenal
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551941/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-356
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