High IL2RA mRNA expression is an independent adverse prognostic biomarker in core binding factor and intermediate-risk acute myeloid leukemia

BACKGROUND: Elevated protein expressions of CD markers such as IL2RA/CD25, CXCR4/CD184, CD34 and CD56 are associated with adverse prognosis in acute myeloid leukemia (AML). However, the prognostic value of mRNA expressions of these CD markers in AML remains unclear. Through our pilot evaluation, IL2...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Du, Wen, He, Jing, Zhou, Wei, Shu, Simin, Li, Juan, Liu, Wei, Deng, Yun, Lu, Cong, Lin, Shengyan, Ma, Yaokun, He, Yanli, Zheng, Jine, Zhu, Jiang, Bai, Lijuan, Li, Xiaoqing, Yao, Junxia, Hu, Dan, Gu, Shengqing, Li, Huiyu, Guo, Anyuan, Huang, Shiang, Feng, Xiaolan, Hu, Dong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551869/
https://ncbi.nlm.nih.gov/pubmed/31171000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1926-z
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