Protein O-GlcNAcylation Is Essential for the Maintenance of Renal Energy Homeostasis and Function via Lipolysis during Fasting and Diabetes

BACKGROUND: Energy metabolism in proximal tubular epithelial cells (PTECs) is unique, because ATP production largely depends on lipolysis in both the fed and fasting states. Furthermore, disruption of renal lipolysis is involved in the pathogenesis of diabetic tubulopathy. Emerging evidence suggests...

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Detaylı Bibliyografya
Yayımlandı:J Am Soc Nephrol
Asıl Yazarlar: Sugahara, Sho, Kume, Shinji, Chin-Kanasaki, Masami, Tomita, Issei, Yasuda-Yamahara, Mako, Yamahara, Kosuke, Takeda, Naoko, Osawa, Norihisa, Yanagita, Motoko, Araki, Shin-ichi, Maegawa, Hiroshi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Nephrology 2019
Konular:
Basic Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551777/
https://ncbi.nlm.nih.gov/pubmed/31043434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018090950
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