SAT-036 Extracellular Domain Calcium-Sensing Receptor (CaSR) Mutations Leading to Hypercalcemic and Hypocalcemic Disorders Cluster at the Homodimeric Interface

The calcium-sensing receptor (CaSR) is a homodimeric G-protein coupled receptor that plays a pivotal role in extracellular Ca(2+) (Ca(2+)(e)) homeostasis, and loss- and gain-of-function mutations of the CaSR cause familial hypocalciuric hypercalcemia type 1 (FHH1) and autosomal dominant hypocalcemia...

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Detaylı Bibliyografya
Yayımlandı:J Endocr Soc
Asıl Yazarlar: Olesen, Mie, Gorvin, Caroline, Thakker, Rajesh, Hannan, Fadil
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Endocrine Society 2019
Konular:
Non-Steroid Hormone Signaling
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551669/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-036
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