SAT-201 Diet-Induced Obesity and Prenatal Androgen Exposure Increase Transgenerational Susceptibility to Metabolic Dysfunction in Male Adult Offspring

It is suggested that intrauterine environment play a role in the development of PCOS, and that first generation (F1) male offspring of the prenatal androgenized (PNA)-mice model exhibit metabolic dysfunction such as increased body weight and insulin resistance. Whether prenatal androgenisation, with...

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Vydáno v:J Endocr Soc
Hlavní autoři: Lu, Haojiang, Risal, Sanjiv, Manti, Maria, Fornes, Romina, Zhao, Zhiyi, Lindgren, Eva, Benrick, Anna, Deng, Qiaolin, Stener-Victorin, Elisabet
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2019
Témata:
Reproductive Endocrinology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551649/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-201
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