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Hepatocyte Nuclear Factor 4 alpha (HNF4α) Activation is Essential for Termination of Liver Regeneration

Hepatocyte Nuclear Factor 4 alpha (HNF4α) is critical for hepatic differentiation. Recent studies have highlighted its role in inhibition of hepatocyte proliferation and tumor suppression. However, the role of HNF4α in liver regeneration is not known. We hypothesized that hepatocytes modulate HNF4α...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Huck, Ian, Gunewardena, Sumedha, Espanol-Suner, Regina, Willenbring, Holger, Apte, Udayan
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551324/
https://ncbi.nlm.nih.gov/pubmed/30520062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30405
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