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MON-413 First Reported Case of Combined High-Dose Mifepristone Therapy and Oral Contraceptive in Inducing Reversible Cholestatic Hepatitis in a Patient with Cushing Disease

Background: Cushing syndrome is predisposed to hepatocellular disease due to increased visceral fat resulting in NAFLD, and direct effects of medical therapy, notably ketoconazole. Mifepristone (MIFE) (a competitive glucocorticoid receptor antagonist) is a CYP3A4 inhibitor, whereas loestrin (an oral...

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Vydáno v:J Endocr Soc
Hlavní autoři: Youssef, Nancy, Reynolds, Justin, Yuen, Kevin
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551021/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-MON-413
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