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MON-LB039 Developmental Programming: Prenatal Testosterone Excess Induces Endoplasmic Reticulum (ER) Stress in the Metabolic Tissues of the Female Sheep

Prenatal exposure to excess testosterone (T) programs peripheral insulin resistance (IR) and dyslipidemia along with tissue-specific changes in ectopic lipid accumulation, oxidative stress and IR in liver and muscle, and inflammation, oxidative stress, and reduced adipogenesis, differentiation, and...

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Опубликовано в: :J Endocr Soc
Главные авторы: Puttabyatappa, Muraly, Padmanabhan, Vasantha
Формат: Artigo
Язык:Inglês
Опубликовано: Endocrine Society 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550894/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-MON-LB039
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