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MON-LB022 Gelesis Novel, Non-Systemic, Superabsorbent Hydrogel Improves Intestinal Barrier Function in Mice with DSS Induced Colitis

BACKGROUND: Intestinal barrier dysfunction exists when the epithelial tight-junctions are disrupted and permit translocation of bacterial lipopolysaccharides into the blood. The resulting endotoxemia cause systemic low-grade inflammation that contributes to the development of comorbidities associate...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Silvestri, Alessandra, Lyng, Gregory, Parello, Caitlin, Graham, Sean, Chiquette, Elaine, Sannino, Alessandro, Rescigno, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550881/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-MON-LB022
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