MON-LB019 Setmelanotide (RM-493) Reduces Food Intake and Rapidly Induces Weight Loss in a Mouse Model of Alström Syndrome

Introduction  Alström syndrome (AS) is an autosomal recessive ciliopathy caused by mutations in ALMS1, which encodes a protein that localizes to centrosomes and basal bodies of primary cilia. Early emergence of obesity in patients with AS suggests a key r...

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Bibliografiska uppgifter
I publikationen:J Endocr Soc
Huvudupphovsmän: Stephenson, Erin, McAllan, Liam, Stayton, Amanda, Han, Joan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Endocrine Society 2019
Ämnen:
Adipose Tissue, Appetite, and Obesity
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550858/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-MON-LB019
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