MON-460 Pasireotide Treatment Inhibits Cytokine Release from Pituitary Adenoma-Associated Fibroblasts: Is This Mechanism Playing a Key Role in Its Effect?

Introduction: Tumour-associated fibroblasts (TAFs) are important elements of the tumour microenvironment (TME) well-studied in several cancers, but their role in pituitary adenomas (PAs) has never been shown. We aimed to study the role of TAFs in PAs and its response to somatostatin analogues (SSA)....

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Marques, Pedro, Barry, Sayka, Carlsen, Eivind, Collier, David, Ronaldson, Amy, Awad, Sherine, Dorward, Neil, Grieve, Joan, Balkwill, Frances, Korbonits, Márta
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2019
Assuntos:
Neuroendocrinology and Pituitary
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550646/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-MON-460
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