Clonorchis sinensis excretory-secretory products increase malignant characteristics of cholangiocarcinoma cells in three-dimensional co-culture with biliary ductal plates

Clonorchis sinensis is a carcinogenic human liver fluke, prolonged infection which provokes chronic inflammation, epithelial hyperplasia, periductal fibrosis, and even cholangiocarcinoma (CCA). These effects are driven by direct physical damage caused by the worms, as well as chemical irritation fro...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Pathog
Hauptverfasser: Won, Jihee, Cho, Youngkyu, Lee, Dahyun, Jeon, Bo Young, Ju, Jung-Won, Chung, Seok, Pak, Jhang Ho
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550432/
https://ncbi.nlm.nih.gov/pubmed/31121000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007818
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