Clonorchis sinensis excretory-secretory products increase malignant characteristics of cholangiocarcinoma cells in three-dimensional co-culture with biliary ductal plates

Clonorchis sinensis is a carcinogenic human liver fluke, prolonged infection which provokes chronic inflammation, epithelial hyperplasia, periductal fibrosis, and even cholangiocarcinoma (CCA). These effects are driven by direct physical damage caused by the worms, as well as chemical irritation fro...

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Bibliografiske detaljer
Udgivet i:PLoS Pathog
Main Authors: Won, Jihee, Cho, Youngkyu, Lee, Dahyun, Jeon, Bo Young, Ju, Jung-Won, Chung, Seok, Pak, Jhang Ho
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550432/
https://ncbi.nlm.nih.gov/pubmed/31121000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007818
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