Enhanced histamine-induced itch in diacylglycerol kinase iota knockout mice

Subsets of small-diameter dorsal root ganglia (DRG) neurons detect pruritogenic (itch-causing) and algogenic (pain-causing) stimuli and can be activated or sensitized by chemical mediators. Many of these chemical mediators activate receptors that are coupled to lipid hydrolysis and diacylglycerol (D...

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Udgivet i:PLoS One
Main Authors: Bartsch, Victoria Brings, Niehaus, Jesse K., Taylor-Blake, Bonnie, Zylka, Mark J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550402/
https://ncbi.nlm.nih.gov/pubmed/31167004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217819
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