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Expanding Pathobiological Mechanisms in Hypertrophic Cardiomyopathy to Explain Heterogeneity: JACC Review Topic of the Week

Hypertrophic cardiomyopathy (HCM) has been considered a heterogeneous cardiac disease ascribed solely to single sarcomere gene mutations. Limitations of this hypothesis suggest that sarcomere mutations alone do not adequately explain all HCM clinical and pathobiologic features. Disease-causing sarco...

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Detalhes bibliográficos
Publicado no:J Am Coll Cardiol
Main Authors: Maron, Barry J., Maron, Martin S., Maron, Bradley A., Loscalzo, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550351/
https://ncbi.nlm.nih.gov/pubmed/31000001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2019.01.061
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