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PGC1α/CEBPB/CPT1A axis promotes radiation resistance of nasopharyngeal carcinoma through activating fatty acid oxidation

The PPAR coactivator‐1α (PGC1α) is an important transcriptional co‐activator in control of fatty acid metabolism. Mitochondrial fatty acid oxidation (FAO) is the primary pathway for the degradation of fatty acids and promotes NADPH and ATP production. Our previous study demonstrated that upregulatio...

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Détails bibliographiques
Publié dans:Cancer Sci
Auteurs principaux: Du, Qianqian, Tan, Zheqiong, Shi, Feng, Tang, Min, Xie, Longlong, Zhao, Lin, Li, Yueshuo, Hu, Jianmin, Zhou, Min, Bode, Ann, Luo, Xiangjian, Cao, Ya
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550130/
https://ncbi.nlm.nih.gov/pubmed/30945396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14011
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