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PGC1α/CEBPB/CPT1A axis promotes radiation resistance of nasopharyngeal carcinoma through activating fatty acid oxidation

The PPAR coactivator‐1α (PGC1α) is an important transcriptional co‐activator in control of fatty acid metabolism. Mitochondrial fatty acid oxidation (FAO) is the primary pathway for the degradation of fatty acids and promotes NADPH and ATP production. Our previous study demonstrated that upregulatio...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Du, Qianqian, Tan, Zheqiong, Shi, Feng, Tang, Min, Xie, Longlong, Zhao, Lin, Li, Yueshuo, Hu, Jianmin, Zhou, Min, Bode, Ann, Luo, Xiangjian, Cao, Ya
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550130/
https://ncbi.nlm.nih.gov/pubmed/30945396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14011
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