A single KH domain in Bicaudal-C links mRNA binding and translational repression functions to maternal development

Bicaudal-C (Bicc1) is a conserved RNA-binding protein that represses the translation of selected mRNAs to control development. In Xenopus embryos, Bicc1 binds and represses specific maternal mRNAs to control anterior-posterior cell fates. However, it is not known how Bicc1 binds its RNA targets or h...

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Bibliographic Details
Published in:Development
Main Authors: Dowdle, Megan E., Park, Sookhee, Blaser Imboden, Susanne, Fox, Catherine A., Houston, Douglas W., Sheets, Michael D.
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550016/
https://ncbi.nlm.nih.gov/pubmed/31023875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.172486
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