Enhanced anticancer effects of a methylation inhibitor by inhibiting a novel DNMT1 target, CEP 131, in cervical cancer

Methylation is a primary epigenetic mechanism regulating gene expression. 5-aza-2′-deoxycytidine is an FDA-approved drug prescribed for treatment of cancer by inhibiting DNA-Methyl-Transferase 1 (DNMT1). Results of this study suggest that prolonged treatment with 5-aza-2′-deoxycytidine could induce...

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Publicado no:BMB Rep
Main Authors: Kim, Dong Hyun, Kim, Hye-Min, Huong, Pham Thi Thu, Han, Ho-Jin, Hwang, Joonsung, Cha-Molstad, Hyunjoo, Lee, Kyung Ho, Ryoo, In-Ja, Kim, Kyoon Eon, Huh, Yang Hoon, Ahn, Jong Seog, Kwon, Yong Tae, Soung, Nak-Kyun, Kim, Bo Yeon
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549914/
https://ncbi.nlm.nih.gov/pubmed/31068247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2019.52.5.055
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