Discovery of Furanoquinone Derivatives as a Novel Class of DNA Polymerase and Gyrase Inhibitors for MRSA Eradication in Cutaneous Infection

Methicillin-resistant Staphylococcus aureus (MRSA) is the primary microbe responsible for skin infections that are particularly difficult to eradicate. This study sought to inhibit planktonic and biofilm MRSA using furanoquinone-derived compounds containing imine moiety. A total of 19 furanoquinone...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Yang, Shih-Chun, Tang, Kai-Wei, Lin, Chih-Hung, Alalaiwe, Ahmed, Tseng, Chih-Hua, Fang, Jia-You
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549599/
https://ncbi.nlm.nih.gov/pubmed/31191504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.01197
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