Elucidating a false-negative MYC break-apart fluorescence in situ hybridization probe study by next-generation sequencing in a patient with high-grade B-cell lymphoma with IGH/MYC and IGH/BCL2 rearrangements

The identification of MYC rearrangements in several mature B-cell neoplasms is critical for diagnostic and prognostic purposes. Commercially available fluorescence in situ hybridization (FISH) probe sets, including IGH/MYC dual-color dual-fusion (D-FISH) and MYC break-apart probes (BAPs), serve as t...

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Dettagli Bibliografici
Pubblicato in:Cold Spring Harb Mol Case Stud
Autori principali: Peterson, Jess F., Pitel, Beth A., Smoley, Stephanie A., Vasmatzis, George, Smadbeck, James B., Greipp, Patricia T., Ketterling, Rhett P., Macon, William R., Baughn, Linda B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2019
Soggetti:
Research Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549546/
https://ncbi.nlm.nih.gov/pubmed/31160360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a004077
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