Preferential Reactivity of Dipeptidyl Peptidase-IV Inhibitor-Associated Bullous Pemphigoid Autoantibodies to the Processed Extracellular Domains of BP180

Bullous pemphigoid (BP) is a common autoimmune blistering disease in which autoantibodies target the hemidesmosomal components BP180 and/or BP230 in basal keratinocytes. In BP, 80 to 90% of autoantibodies target the juxtamembranous extracellular non-collagenous 16th A (NC16A) domain of BP180. Recent...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Mai, Yosuke, Nishie, Wataru, Izumi, Kentaro, Shimizu, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549357/
https://ncbi.nlm.nih.gov/pubmed/31191560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01224
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