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COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining

BACKGROUND: Pharmacological treatment of complex diseases using more than two drugs is commonplace in the clinic due to better efficacy, decreased toxicity and reduced risk for developing resistance. However, many of these higher-order treatments have not undergone any detailed preceding in vitro ev...

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Publicat a:BMC Bioinformatics
Autors principals: Chantzi, Efthymia, Jarvius, Malin, Niklasson, Mia, Segerman, Anna, Gustafsson, Mats G.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549340/
https://ncbi.nlm.nih.gov/pubmed/31164078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2908-0
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