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Pinin protects astrocytes from cell death after acute ischemic stroke via maintenance of mitochondrial anti-apoptotic and bioenergetics functions

BACKGROUND: Stroke is the second most common cause of deaths worldwide. After an ischemic stroke, the proliferated reactive astrocytes in the peri-infarct areas play a beneficial role in neuronal survival. As such, astrocytes have gradually become a target for neuroprotection in stroke. The present...

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Bibliografische gegevens
Gepubliceerd in:J Biomed Sci
Hoofdauteurs: Mukda, Sujira, Tsai, Ching-Yi, Leu, Steve, Yang, Jenq-Lin, Chan, Samuel H. H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549339/
https://ncbi.nlm.nih.gov/pubmed/31167655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-019-0538-5
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