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VWC2 Increases Bone Formation Through Inhibiting Activin Signaling

By a bioinformatics approach, we have identified a novel cysteine knot protein member, VWC2 (von Willebrand factor C domain containing 2) previously known as Brorin. Since Brorin has been proposed to function as a bone morphogenetic protein (BMP) antagonist, we investigated the binding of Brorin/VWC...

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Detalhes bibliográficos
Publicado no:Calcif Tissue Int
Main Authors: Almehmadi, Ahmad, Ohyama, Yoshio, Kaku, Masaru, Alamoudi, Ahmed, Husein, Dina, Katafuchi, Michitsuna, Mishina, Yuji, Mochida, Yoshiyuki
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549224/
https://ncbi.nlm.nih.gov/pubmed/30074079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-018-0462-9
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