Loss of transglutaminase 2 sensitizes for diet-induced obesity-related inflammation and insulin resistance due to enhanced macrophage c-Src signaling

Transglutaminase 2 (TG2) is a multifunctional protein that promotes clearance of apoptotic cells (efferocytosis) acting as integrin β(3) coreceptor. Accumulating evidence indicates that defective efferocytosis contributes to the development of chronic inflammatory diseases. Obesity is characterized...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Sághy, Tibor, Köröskényi, Krisztina, Hegedűs, Krisztina, Antal, Miklós, Bankó, Csaba, Bacsó, Zsolt, Papp, Attila, Stienstra, Rinke, Szondy, Zsuzsa
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549190/
https://ncbi.nlm.nih.gov/pubmed/31165747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1677-z
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