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The nucleoporin ELYS regulates nuclear size by controlling NPC number and nuclear import capacity

How intracellular organelles acquire their characteristic sizes is a fundamental question in cell biology. Given stereotypical changes in nuclear size in cancer, it is important to understand the mechanisms that control nuclear size in human cells. Using a high‐throughput imaging RNAi screen, we ide...

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Podrobná bibliografie
Vydáno v:EMBO Rep
Hlavní autoři: Jevtić, Predrag, Schibler, Andria C, Wesley, Chase C, Pegoraro, Gianluca, Misteli, Tom, Levy, Daniel L
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549122/
https://ncbi.nlm.nih.gov/pubmed/31085625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201847283
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