Cytokeratin 18 regulates the transcription and alternative splicing of apoptotic-related genes and pathways in HeLa cells

Cytokeratin 18 (CK18), one of the major components of intermediate filaments (IF) in simple epithelial cells, undergoes caspase-mediated cleavage upon epithelial cell necrosis and apoptosis. CK18 has been used as a biomarker of several cancers and has been reported to be dysregulated in cervical can...

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Gepubliceerd in:Oncol Rep
Hoofdauteurs: Cheng, Yi, Qin, Kai, Huang, Nan, Zhou, Zhipeng, Xiong, Huihua, Zhao, Jing, Zhang, Yi, Yu, Shiying
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549092/
https://ncbi.nlm.nih.gov/pubmed/31115582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2019.7166
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