Genetic data and cognitively defined late-onset Alzheimer’s disease subgroups

Categorizing people with late-onset Alzheimer’s disease into biologically coherent subgroups is important for personalized medicine. We evaluated data from five studies (total n = 4050, of whom 2431 had genome-wide single-nucleotide polymorphism (SNP) data). We assigned people to cognitively defined...

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Published in:Mol Psychiatry
Main Authors: Mukherjee, Shubhabrata, Mez, Jesse, Trittschuh, Emily H., Saykin, Andrew J., Gibbons, Laura E., Fardo, David W., Wessels, Madeline, Bauman, Julianna, Moore, Mackenzie, Choi, Seo-Eun, Gross, Alden L., Rich, Joanne, Louden, Diana K. N., Sanders, R. Elizabeth, Grabowski, Thomas J., Bird, Thomas D., McCurry, Susan M., Snitz, Beth E., Kamboh, M. Ilyas, Lopez, Oscar L., De Jager, Philip L., Bennett, David A., Keene, C. Dirk, Larson, Eric B., Crane, Paul K.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548676/
https://ncbi.nlm.nih.gov/pubmed/30514930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-018-0298-8
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