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Diastereodivergent Synthesis of Hexahydro-6H-benzo[c]chromen-6-one Derivatives Catalyzed by Modularly Designed Organocatalysts

The diastereodivergent synthesis of hexahydro-6H-benzo[c]chromen-6-one with good to high diastereoselectivities (up to 98:2 dr) and enantioselectivities (up to >99% ee) has been achieved by using a domino Michael/Michael/hemiacetalization reaction between trans-2-hydroxy-β-nitrostyrenes and trans...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Jakkampudi, Satish, Parella, Ramarao, Arman, Hadi D., Zhao, John C.-G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548622/
https://ncbi.nlm.nih.gov/pubmed/30895663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201806447
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