E-cadherin represses anchorage-independent growth in sarcomas through both signaling and mechanical mechanisms

E-cadherin, an epithelial-specific cell-cell adhesion molecule, plays multiple roles in maintaining adherens junctions, regulating migration and invasion, and mediating intracellular signaling. Downregulation of E-cadherin is a hallmark of epithelial-mesenchymal transition (EMT) and correlates with...

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Publicado en:Mol Cancer Res
Autores principales: Jolly, Mohit Kumar, Ware, Kathryn E., Xu, Shengnan, Gilja, Shivee, Shetler, Samantha, Yang, Yanjun, Wang, Xueyang, Austin, R. Garland, Runyambo, Daniella, Hish, Alexander J., DeWitt, Suzanne Bartholf, George, Jason T., Kreulen, R. Timothy, Boss, Mary-Keara, Lazarides, Alexander L., Kerr, David L., Gerber, Drew G., Sivaraj, Dharshan, Armstrong, Andrew J., Dewhirst, Mark W., Eward, William C., Levine, Herbert, Somarelli, Jason A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548594/
https://ncbi.nlm.nih.gov/pubmed/30862685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-0763
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