Dissociating orexin-dependent and -independent functions of orexin neurons using novel Orexin-Flp knock-in mice

Uninterrupted arousal is important for survival during threatening situations. Activation of orexin/hypocretin neurons is implicated in sustained arousal. However, orexin neurons produce and release orexin as well as several co-transmitters including dynorphin and glutamate. To disambiguate orexin-d...

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Pubblicato in:eLife
Autori principali: Chowdhury, Srikanta, Hung, Chi Jung, Izawa, Shuntaro, Inutsuka, Ayumu, Kawamura, Meiko, Kawashima, Takashi, Bito, Haruhiko, Imayoshi, Itaru, Abe, Manabu, Sakimura, Kenji, Yamanaka, Akihiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2019
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548533/
https://ncbi.nlm.nih.gov/pubmed/31159922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44927
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