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Palmitate is not an effective fuel for pancreatic islets and amplifies insulin secretion independent of calcium release from endoplasmic reticulum

The aim of the study was to determine the acute contribution of fuel oxidation in mediating the increase in insulin secretion rate (ISR) in response to fatty acids. Measures of mitochondrial metabolism, as reflected by oxygen consumption rate (OCR) and cytochrome c reduction, calcium signaling, and...

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Vydáno v:Islets
Hlavní autoři: Kuok, Iok Teng, Rountree, Austin M., Jung, Seung-Ryoung, Sweet, Ian R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548485/
https://ncbi.nlm.nih.gov/pubmed/31084524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19382014.2019.1601490
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