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Nanoemulsion-Based Delivery of Fluorescent PARP Inhibitors in Mouse Models of Small Cell Lung Cancer

The preclinical potential of many diagnostic and therapeutic small molecules is limited by their rapid washout kinetics and consequently modest pharmacological performances. In several cases, these could be improved by loading the small molecules into nanoparticulates, improving blood half-life, in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Bioconjug Chem
Hauptverfasser: Gonzales, Junior, Kossatz, Susanne, Roberts, Sheryl, Pirovano, Giacomo, Brand, Christian, Pérez-Medina, Carlos, Donabedian, Patrick, de la Cruz, M. Jason, Mulder, Willem J. M., Reiner, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548450/
https://ncbi.nlm.nih.gov/pubmed/30354077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.8b00640
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