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Mapping a Systematic Ribozyme Fitness Landscape Reveals a Frustrated Evolutionary Network for Self-Aminoacylating RNA
[Image: see text] Molecular evolution can be conceptualized as a walk over a “fitness landscape”, or the function of fitness (e.g., catalytic activity) over the space of all possible sequences. Understanding evolution requires knowing the structure of the fitness landscape and identifying the viable...
Na minha lista:
| Foilsithe in: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American Chemical
Society
2019
|
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6548421/ https://ncbi.nlm.nih.gov/pubmed/30912655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b13298 |
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