ZAP’s stress granule localization is correlated with its antiviral activity and induced by virus replication

Cellular antiviral programs encode molecules capable of targeting multiple steps in the virus lifecycle. Zinc-finger antiviral protein (ZAP) is a central and general regulator of antiviral activity that targets pathogen mRNA stability and translation. ZAP is diffusely cytoplasmic, but upon infection...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Principais autores: Law, Lok Man John, Razooky, Brandon S., Li, Melody M. H., You, Shihyun, Jurado, Andrea, Rice, Charles M., MacDonald, Margaret R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548403/
https://ncbi.nlm.nih.gov/pubmed/31116799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007798
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