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Anchoring high concentrations of SynGAP at postsynaptic densities via liquid-liquid phase separation
SynGAP, encoded by SYNGAP1, is a Ras/Rap GTPase activator specifically expressed in the nervous systems. SynGAP is one of the most abundant proteins in the postsynaptic densities (PSDs) of excitatory synapses and acts as a critical synaptic activity brake by tuning down synaptic GTPase activities. M...
Gardado en:
| Publicado en: | Small GTPases |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6548289/ https://ncbi.nlm.nih.gov/pubmed/28524815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2017.1320350 |
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