Llwytho...

Mutant p53 amplifies a dynamin-1/APPL1 endosome feedback loop that regulates recycling and migration

Multiple mechanisms contribute to cancer cell progression and metastatic activity, including changes in endocytic trafficking and signaling of cell surface receptors downstream of gain-of-function (GOF) mutant p53. We report that dynamin-1 (Dyn1) is up-regulated at both the mRNA and protein levels i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Biol
Prif Awduron: Lakoduk, Ashley M., Roudot, Philippe, Mettlen, Marcel, Grossman, Heather M., Schmid, Sandra L., Chen, Ping-Hung
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Rockefeller University Press 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548126/
https://ncbi.nlm.nih.gov/pubmed/31043431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201810183
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!