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Predictive Approach Identifies Molecular Targets and Interventions to Restore Angiogenesis in Wounds With Delayed Healing

Impaired angiogenesis is a hallmark of wounds with delayed healing, and currently used therapies to restore angiogenesis have limited efficacy. Here, we employ a computational simulation-based approach to identify influential molecular and cellular processes, as well as protein targets, whose modula...

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Détails bibliographiques
Publié dans:Front Physiol
Auteurs principaux: Nagaraja, Sridevi, Chen, Lin, DiPietro, Luisa A., Reifman, Jaques, Mitrophanov, Alexander Y.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547939/
https://ncbi.nlm.nih.gov/pubmed/31191342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00636
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