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Radiation-dose-dependent functional synergisms between ATM, ATR and DNA-PKcs in checkpoint control and resection in G(2)-phase
Using data generated with cells exposed to ionizing-radiation (IR) in G(2)-phase of the cell cycle, we describe dose-dependent interactions between ATM, ATR and DNA-PKcs revealing unknown mechanistic underpinnings for two key facets of the DNA damage response: DSB end-resection and G(2)-checkpoint a...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6547644/ https://ncbi.nlm.nih.gov/pubmed/31164689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44771-6 |
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